Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 12/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.46 |
| ▸ | MTOR | P42345 | 4/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608346 | 0.88 | PRKDC (0.49) | ALDH1A1PRKDCPIK3CAMTOR | |
| SCHEMBL13334384 | 0.86 | PRKDC (0.48) | PRKDCPIK3CAMTORPDE1BPDE4A | |
| SCHEMBL9608334 | 0.72 | PDE1B (0.52) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL2461370 | 0.72 | PDE1A (0.49) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL9608309 | 0.72 | PDE1B (0.43) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL2455942 | 0.71 | PDE1B (0.48) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL9608316 | 0.71 | PDE1B (0.58) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL2459282 | 0.71 | PDE1B (0.71) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL9608307 | 0.70 | PDE1B (0.48) | ALDH1A1MAPTKDM4EPDE1APDE1B | |
| SCHEMBL9608313 | 0.70 | PDE1B (0.45) | ALDH1A1PDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136013-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES. INC. | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136013-A1 | ORGANIC COMPOUNDS | CYP2C9, CYP2C19, CYP3A4 | ALDH1A1 216/4885MAPT 966/4885KDM4E 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.