Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 19/20 | 0.96 |
| ▸ | BIRC3 | Q13489 | 8/20 | 0.96 |
| ▸ | BIRC2 | Q13490 | 8/20 | 0.96 |
| ▸ | BIRC8 | Q96P09 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611988 | 1.00 | XIAP (0.96) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL13260087 | 1.00 | XIAP (0.96) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL13260088 | 1.00 | XIAP (0.96) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL9611979 | 1.00 | XIAP (0.96) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL12108524 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL19198442 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL13419800 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL12105339 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL1300937 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 | |
| SCHEMBL12464524 | 0.98 | XIAP (1.00) | XIAPBIRC3BIRC2BIRC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |