Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 13/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 8/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728741 | 0.94 | XIAP (0.41) | XIAPBIRC2CASP9BIRC3MEN1 | |
| SCHEMBL13260145 | 0.94 | XIAP (0.41) | XIAPBIRC2CASP9BIRC3MEN1 | |
| SCHEMBL3731477 | 0.88 | TLR2 (0.39) | XIAPBIRC2 | |
| SCHEMBL13260140 | 0.88 | TLR2 (0.39) | XIAPBIRC2 | |
| SCHEMBL3724815 | 0.87 | BIRC2 (0.44) | XIAPBIRC2CASP9BIRC3MEN1 | |
| SCHEMBL13260046 | 0.87 | BIRC2 (0.44) | XIAPBIRC2CASP9BIRC3MEN1 | |
| SCHEMBL13104346 | 0.79 | BIRC2 (0.47) | XIAPBIRC2CASP9BIRC3 | |
| SCHEMBL894486 | 0.78 | XIAP (0.46) | XIAPBIRC2CASP9BIRC3 | |
| SCHEMBL894485 | 0.78 | XIAP (0.46) | XIAPBIRC2CASP9BIRC3 | |
| SCHEMBL1273446 | 0.78 | XIAP (0.50) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |