Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 16/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 9/20 | 0.48 |
| ▸ | BIRC3 | Q13489 | 7/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608937 | 0.84 | XIAP (0.56) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL13260047 | 0.76 | XIAP (0.43) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL3726188 | 0.72 | XIAP (0.40) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL22623336 | 0.70 | XIAP (0.63) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL27310566 | 0.70 | XIAP (0.63) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL23812570 | 0.69 | BIRC2 (0.81) | XIAPBIRC2BIRC3 | |
| SCHEMBL23806096 | 0.69 | BIRC2 (0.81) | XIAPBIRC2BIRC3 | |
| SCHEMBL9608965 | 0.68 | XIAP (0.55) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL14421200 | 0.68 | XIAP (0.70) | XIAPBIRC2BIRC3CASP9 | |
| SCHEMBL4315737 | 0.68 | XIAP (0.70) | XIAPBIRC2BIRC3CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |