SCHEMBL9612957

SCHEMBL9612957

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cnccc5C)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.48
CYP17A1 P05093 7/20 0.44
CYP1A2 P05177 6/20 0.44
COMT P21964 1/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
RPS6KA3 P51812 1/20 0.39
ABL1 P00519 3/20 0.38
SLC22A12 Q96S37 1/20 0.36
ACHE P22303 1/20 0.36
MAPK14 Q16539 1/20 0.36
PTGS2 P35354 1/20 0.36
BTK Q06187 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612833 0.96 CYP17A1 (0.49) DHODHCYP17A1CYP1A2COMTCYP11B1
SCHEMBL18174770 0.93 DHODH (0.49) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL9612942 0.93 DHODH (0.52) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174788 0.91 DHODH (0.50) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL9613042 0.91 DHODH (0.46) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174554 0.89 DHODH (0.52) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174773 0.89 DHODH (0.49) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174789 0.88 DHODH (0.46) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174785 0.87 DHODH (0.47) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174771 0.87 DHODH (0.47) DHODHCYP17A1CYP1A2COMTCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed