Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14271633 | 0.88 | SCN9A (0.44) | SCN9ACYP3A4CYP2C19CYP2C9HDAC1 | |
| SCHEMBL9613333 | 0.86 | SCN9A (0.46) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL12190727 | 0.85 | SCN9A (0.45) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL1260037 | 0.85 | SCN9A (0.45) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL13061298 | 0.85 | SCN9A (0.45) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL14384252 | 0.84 | SCN9A (0.44) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL1260393 | 0.84 | SCN9A (0.44) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL1260642 | 0.84 | SCN9A (0.46) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL12190726 | 0.83 | SCN9A (0.44) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 | |
| SCHEMBL12190720 | 0.83 | SCN9A (0.44) | SCN9AALDH1A1NPSR1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727797-B1 | PROCESS FOR CROSS COUPLING INDOLES | BOEHRINGER INGELHEIM PHARMA (US) | 2012-05-30 | — | — | EP | disclosed |