Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.63 |
| ▸ | PPARA | Q07869 | 14/20 | 0.63 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696796 | 1.00 | PPARG (0.63) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL9696319 | 0.95 | PPARG (0.61) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL9614213 | 0.90 | PPARA (0.56) | PPARGPPARACTRC | |
| SCHEMBL9696474 | 0.90 | PPARG (0.56) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL9614193 | 0.89 | PPARA (0.73) | PPARGPPARA | |
| SCHEMBL9614218 | 0.89 | PPARA (0.73) | PPARGPPARA | |
| SCHEMBL9695306 | 0.87 | PPARG (0.53) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL10419541 | 0.87 | PPARG (0.72) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL10419347 | 0.86 | PPARG (0.67) | PPARGPPARAPTGESALOX5CTRC | |
| SCHEMBL10419468 | 0.86 | PPARG (0.67) | PPARGPPARAPTGESALOX5CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017435-A1 | OPTICALLY ACTIVE CARBOXYLIC ACIDS AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |