Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.81 |
| ▸ | PPARA | Q07869 | 16/20 | 0.81 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419541 | 0.94 | PPARG (0.72) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL11516826 | 0.90 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL27516719 | 0.85 | PPARG (0.61) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL10420222 | 0.84 | PPARA (0.80) | PPARGPPARA | |
| SCHEMBL10419468 | 0.84 | PPARG (0.67) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL10419347 | 0.84 | PPARG (0.67) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL5523874 | 0.81 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL11345159 | 0.81 | PPARG (0.70) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL8935884 | 0.81 | PPARG (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL289442 | 0.81 | PPARG (0.64) | PPARGPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | claimed |
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |
| EP-0226636-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1987-07-01 | — | — | EP | disclosed |
| WO-1987000521-A2 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1987-01-29 | — | — | WO | disclosed |