Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.58 |
| ▸ | PPARA | Q07869 | 15/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.58 |
| ▸ | PTGES | O14684 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614323 | 0.89 | PPARG (0.58) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858468 | 0.83 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613814 | 0.82 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL10419188 | 0.77 | PPARG (0.52) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9695329 | 0.77 | PPARG (0.52) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614072 | 0.77 | PPARG (0.55) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614074 | 0.77 | PPARG (0.64) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614339 | 0.76 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL1566461 | 0.76 | PPARG (0.63) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613848 | 0.75 | PPARG (0.81) | PPARGPPARAALOX5PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |