Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.61 |
| ▸ | ESRRB | O95718 | 1/20 | 0.57 |
| ▸ | ESRRG | P62508 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194399 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL8375073 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7268989 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7268933 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7263369 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7262810 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL8374584 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7270390 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL10947025 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB | |
| SCHEMBL7271175 | 0.93 | TRPV1 (0.71) | HPGDCA1CA2TRPV1ESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476007-A4 | CATALYTIC ANTIBODIES | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0476007-A1 | CATALYTIC ANTIBODIES | THERAPEUTIC ANTIBODIES INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015134-A1 | CATALYTIC ANTIBODIES | THERAPEUTIC ANTIBODIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |