Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.39 |
| ▸ | NPY1R | P25929 | 6/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307844 | 0.95 | NPY4R (0.37) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| Hydrochloric Acid SCHEMBL7346009 | 0.94 | NPY4R (0.37) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| Trifluoroacetic Acid SCHEMBL7437664 | 0.86 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| Trifluoroacetic Acid SCHEMBL9614803 | 0.82 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| Trifluoroacetic Acid SCHEMBL7318510 | 0.81 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| Trifluoroacetic Acid SCHEMBL9614815 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| Trifluoroacetic Acid SCHEMBL9614806 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| Trifluoroacetic Acid SCHEMBL9614791 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| SCHEMBL30797917 | 0.81 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7306013 | 0.81 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494248-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | — | 1992-08-26 | — | — | EP | disclosed |
| EP-0494248-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-15 | — | — | EP | disclosed |