Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906411 | 0.84 | GAA (0.39) | AURKAKDRAURKBCYP1A2METAP2 | |
| SCHEMBL25526842 | 0.81 | AURKA (0.49) | AURKAKDRAURKBCFTRULK1 | |
| SCHEMBL15938761 | 0.79 | AURKA (0.48) | AURKAKDRAURKBCYP1A2METAP2 | |
| SCHEMBL3969157 | 0.79 | XPO1 (0.38) | AURKAKDRAURKBCYP1A2METAP2 | |
| SCHEMBL2015792 | 0.79 | AURKA (0.48) | AURKAKDRAURKBCYP1A2CFTR | |
| SCHEMBL15938384 | 0.79 | AURKA (0.50) | AURKAKDRAURKBCYP1A2METAP2 | |
| SCHEMBL25199470 | 0.77 | AURKA (0.49) | AURKAKDRAURKBCFTRULK1 | |
| SCHEMBL31726555 | 0.77 | AURKA (0.49) | AURKAKDRAURKBCFTRULK1 | |
| SCHEMBL30397380 | 0.75 | KDR (0.58) | AURKAKDRAURKBCFTRULK1 | |
| SCHEMBL25207187 | 0.75 | KDR (0.58) | AURKAKDRAURKBCFTRULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4117367-A | — | — | None | — | — | JP | disclosed |
| JP-H04117367-A | FLUOROALKYL GROUP-CONTAINING PYRIMIDINE DERIVATIVE AND PRODUCTION THEREOF | AGENCY OF IND SCIENCE & TECHNOL | 1992-04-17 | — | — | JP | disclosed |