SCHEMBL9615641

SCHEMBL9615641

CCCC1CCC(C2CCC(c3ccc(F)c(C(F)(F)F)c3)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
POLQ O75417 1/20 0.38
KCNN4 O15554 1/20 0.37
RXRA P19793 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37
DRD2 P14416 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRNB2 P17787 1/20 0.35
ADRA2C P18825 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615642 1.00 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9615640 1.00 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8961284 0.89 KDM1A (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8961279 0.89 KDM1A (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8961337 0.89 KDM1A (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL12314616 0.86 CYP2C9 (0.48) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL548067 0.86 CYP2C9 (0.48) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL548068 0.86 CYP2C9 (0.48) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9499838 0.86 CYP2C9 (0.48) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL548069 0.86 CYP2C9 (0.48) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4054138-A None JP disclosed
JP-H0454138-A FLUORINATED COMPOUND CHISSO CORP 1992-02-21 JP disclosed