Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10590830 | 1.00 | PAOX (0.50) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL10590828 | 1.00 | PAOX (0.50) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL7628868 | 0.97 | PAOX (0.48) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL9554433 | 0.97 | PAOX (0.48) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL301894 | 0.97 | — | — | |
| Acetic Acid SCHEMBL4397846 | 0.97 | CYP1A2 (0.53) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL9116471 | 0.97 | CYP1A2 (0.53) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL707699 | 0.97 | CYP1A2 (0.53) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL9807766 | 0.97 | CYP1A2 (0.53) | PAOXCYP1A2GABRR1LMNATHRB | |
| Acetic Acid SCHEMBL8864217 | 0.94 | PAOX (0.46) | PAOXCYP1A2GABRR1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108878-A | Continuous processing in multicompartment apparatus | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| US-5066570-A | Desilvering by passing through multicompartment tank filled with different solutions in absence of air | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |