Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615732 | 1.00 | TSHR (0.41) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9834667 | 0.89 | PDE4B (0.52) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9834662 | 0.89 | PDE4B (0.52) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10569609 | 0.88 | TDP1 (0.52) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10569610 | 0.88 | TDP1 (0.52) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10725789 | 0.83 | MAPT (0.48) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10725781 | 0.83 | MAPT (0.48) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10566644 | 0.82 | PDE4B (0.51) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10566643 | 0.82 | PDE4B (0.51) | TSHRTDP1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10726287 | 0.81 | MAPT (0.46) | TSHRTDP1MAPK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4159266-A | — | — | None | — | — | JP | disclosed |
| JP-H04159266-A | PYRIMIDINONE DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1992-06-02 | — | — | JP | disclosed |