Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22858221 | 0.67 | KDM4E (0.38) | CYP3A4MAPK1TSHRALDH1A1TDP1 | |
| SCHEMBL5040022 | 0.65 | — | — | |
| SCHEMBL4803381 | 0.63 | HSD17B10 (0.34) | CYP3A4MAPK1HSD17B10TSHRALDH1A1 | |
| SCHEMBL11315851 | 0.61 | HPGD (0.43) | CYP3A4MAPK1HSD17B10TSHRALDH1A1 | |
| SCHEMBL9344302 | 0.61 | CYP2A6 (0.44) | CYP3A4MAPK1HSD17B10TSHRALDH1A1 | |
| SCHEMBL29508990 | 0.61 | CYP2A6 (0.44) | CYP3A4MAPK1HSD17B10TSHRALDH1A1 | |
| SCHEMBL911335 | 0.58 | DYRK1A (0.40) | CYP3A4MAPK1DYRK1AHSD17B10TSHR | |
| SCHEMBL21099719 | 0.57 | SMN1; SMN2 (0.72) | CYP3A4MAPK1PIM1TSHRALDH1A1 | |
| SCHEMBL5156416 | 0.57 | — | — | |
| SCHEMBL5154788 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134478-B1 | PROCESS FOR THE PREPARATION OF A PIGMENT BASED ON 4,4',7,7'-TETRACHLOROTHIO-INDIGO | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-04 | — | — | EP | claimed |
| EP-0129690-B1 | PROCESS FOR THE PREPARATION OF 4,4',7,7'-TETRACHLOROTHIOINDIGO PIGMENTS | BAYER AG (DE) | 1989-02-01 | — | — | EP | claimed |
| US-4617403-A | Process for preparing a pigment based on 4,4',7,7'-tetrachlorothioindigo | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | claimed |
| EP-0134478-A2 | Process for the preparation of a pigment based on 4,4',7,7'-tetrachlorothio-indigo | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0056868-B1 | PROCESS FOR THE PREPARATION OF DEEPLY COLORED 4,4',7,7'-TETRACHLORO THIOINDIGO PIGMENTS | BASF Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | claimed |
| EP-0066806-B1 | PROCESS FOR THE PREPARATION OF 4,7-DICHLORO-3-HYDROXY-THIONAPHTHENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-11 | — | — | EP | claimed |
| US-4456762-A | Process for the preparation of 4,7-dichloro-3-hydroxy-thionaphthene | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | claimed |
| US-4431824-A | Preparation of 4,4',7,7'-tetrachlorothioindigo pigments of high color strength | BASF AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | claimed |
| EP-0066806-A1 | Process for the preparation of 4,7-dichloro-3-hydroxy-thionaphthene | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-15 | — | — | EP | claimed |
| EP-0056868-A2 | Process for the preparation of deeply colored 4,4',7,7'-tetrachloro thioindigo pigments | BASF Aktiengesellschaft (DE) | 1982-08-04 | — | — | EP | claimed |
| EP-0056867-A2 | Process for the preparation of 4,4'-7,7'-tetrachloro thioindigo | BASF Aktiengesellschaft (DE) | 1982-08-04 | — | — | EP | claimed |
| US-4284789-A | Thio-indigo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | claimed |
| JP-4183751-A | — | — | None | — | — | JP | disclosed |
| JP-H04183751-A | PRODUCTION OF 4,4',7,7'-TETRACHLOROTHIOINDIGO | SUMITOMO SEIKA CHEM CO LTD | 1992-06-30 | — | — | JP | disclosed |
| EP-0134478-B1 | PROCESS FOR THE PREPARATION OF A PIGMENT BASED ON 4,4',7,7'-TETRACHLOROTHIO-INDIGO | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-04 | — | — | EP | disclosed |
| EP-0129690-B1 | PROCESS FOR THE PREPARATION OF 4,4',7,7'-TETRACHLOROTHIOINDIGO PIGMENTS | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |
| US-4284789-A | Thio-indigo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4260778-A | Process for the preparation of thioindigo compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0018008-A2 | Process for the production of glazing-pigment forms of 4,4',7,7'-tetrachlorothio indigo | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
| US-4229583-A | OXIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |