Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183665 | 0.91 | PDE4D (0.39) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9179776 | 0.88 | PDE4D (0.38) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9616208 | 0.88 | MAPT (0.44) | FPR2TSHRSMN1; SMN2USP2MAPT | |
| SCHEMBL9185420 | 0.87 | PDE4D (0.38) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9180422 | 0.86 | PDE4D (0.39) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9185156 | 0.85 | MAPT (0.44) | FPR2TSHRLMNATP53HPGD | |
| SCHEMBL9187653 | 0.85 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9187632 | 0.84 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9186414 | 0.84 | PDE4D (0.40) | PDE4DPDE4BPDE4APDE4CPDE3B | |
| SCHEMBL9186204 | 0.83 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469013-A1 | NOVEL ARYLPYRIDAZINES, THEIR MANUFACTURE, USE AND MEDICAMENTS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1992-02-05 | — | — | EP | disclosed |