Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | MC3R | P41968 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 3/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazinoic Acid SCHEMBL27659395 | 0.83 | KDM4E (0.91) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL23757 | 0.83 | — | — | |
| Pyrazinoic Acid SCHEMBL29651929 | 0.83 | — | — | |
| SCHEMBL29578557 | 0.83 | ATR (0.53) | KDM4ENAPRTTSHRPRKCIATR | |
| SCHEMBL65106 | 0.83 | ATR (0.53) | KDM4ENAPRTTSHRPRKCIATR | |
| Pyrazinoic Acid SCHEMBL8341710 | 0.81 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL9478226 | 0.81 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL10349317 | 0.81 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL6631652 | 0.81 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazinoic Acid SCHEMBL8978502 | 0.81 | KDM4E (0.95) | KDM4ENAPRTHCAR2ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118937-A | Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules | FINNIGAN MAT GMBH (DE) | 1992-06-02 | — | — | US | disclosed |