SCHEMBL9616247

SCHEMBL9616247

O=C(O)c1cnccc1NO

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 19/20 0.55
KDM6B O15054 8/20 0.50
KDM4D Q6B0I6 5/20 0.50
KDM4E B2RXH2 2/20 0.50
KDM4A O75164 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
EGLN3 Q9H6Z9 1/20 0.42
KDM5B Q9UGL1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20982055 0.84 KDM4C (0.70) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL188821 0.84 KDM4C (0.55) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL19611328 0.84 KDM4C (0.55) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL3823398 0.84 KDM4C (0.76) KDM4CKDM6BKDM4DKDM4EKDM4A
Acetone SCHEMBL2032550 0.79 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL4429003 0.79 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL5010679 0.79 KDM4C (0.50) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL31620734 0.79 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A
Acetone SCHEMBL15923153 0.78 KDM4C (0.53) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL30545176 0.78 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118937-A Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules FINNIGAN MAT GMBH (DE) 1992-06-02 US claimed