SCHEMBL9616256

SCHEMBL9616256

FC(F)(F)C1(C(F)(F)F)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258015 0.86 PDK2 (0.62) PDK2
SCHEMBL6856357 0.86 PDK2 (0.62) PDK2
SCHEMBL9732686 0.80 PDK2 (0.40) PDK2
SCHEMBL29617163 0.80 PDK2 (0.40) PDK2
SCHEMBL8813920 0.80 HTR2A (0.45) PDK2
SCHEMBL8816141 0.78 PDK2 (0.48) PDK2
SCHEMBL14691557 0.78 MAPT (0.41) PDK2
SCHEMBL13308755 0.75 PDK2 (0.62) PDK2
SCHEMBL30612856 0.73 PDK2 (0.48) PDK2
SCHEMBL15203037 0.73 PDK2 (0.76) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504322-A1 PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS. DU PONT (US) 1992-09-23 EP claimed
WO-1991009025-A2 PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-27 WO claimed