Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958241 | 0.78 | KMT2A (0.50) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL953947 | 0.78 | KMT2A (0.50) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL4396455 | 0.78 | KMT2A (0.50) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| Bromide SCHEMBL4505514 | 0.77 | KMT2A (0.49) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| Bromide SCHEMBL4505510 | 0.77 | KMT2A (0.49) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| Hydrochloric Acid SCHEMBL10869034 | 0.77 | KMT2A (0.49) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL960975 | 0.74 | KMT2A (0.46) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL962721 | 0.74 | KMT2A (0.46) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL962720 | 0.74 | KMT2A (0.46) | KMT2ALMNAMEN1CYP2D6HRH1 | |
| SCHEMBL960974 | 0.74 | KMT2A (0.46) | KMT2ALMNAMEN1CYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505376-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-09-30 | — | — | EP | disclosed |