Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | PTGES | O14684 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550836 | 0.87 | CYP19A1 (0.65) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL8979118 | 0.87 | CYP19A1 (0.65) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL8978983 | 0.81 | CYP19A1 (0.60) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL9504767 | 0.80 | CYP19A1 (1.00) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL8942521 | 0.80 | CYP19A1 (0.82) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| Ns-398 SCHEMBL29368077 | 0.80 | CYP19A1 (1.00) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| Ns-398 SCHEMBL214213 | 0.80 | CYP19A1 (1.00) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL8979070 | 0.79 | CYP19A1 (0.55) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| SCHEMBL9559066 | 0.79 | CYP19A1 (0.55) | CYP19A1ALDH1A1MAPTPTGS2MEN1 | |
| Ns-398 SCHEMBL9505669 | 0.79 | CYP19A1 (0.98) | CYP19A1ALDH1A1MAPTPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4283555-A | — | — | None | — | — | JP | disclosed |
| JP-H04283555-A | 4-SUBSTITUTED SULFONANILIODE COMPOUND | TAISHO PHARMACEUT CO LTD | 1992-10-08 | — | — | JP | disclosed |