SCHEMBL9618205

SCHEMBL9618205

CO[Si](CC12C(=O)OC(=O)C1C1C=CC2C1)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7195579 0.80 KDM4E (0.35) KDM4EPOLBTDP1L3MBTL1
SCHEMBL11571423 0.77 KDM4E (0.35) KDM4EPOLBTDP1
SCHEMBL11582696 0.75 KDM4E (0.32) KDM4ETDP1
SCHEMBL2196208 0.74 KDM4E (0.33) KDM4ETDP1
SCHEMBL19668585 0.73 KDM4E (0.30) KDM4E
SCHEMBL13483357 0.73 KDM4E (0.40) KDM4ETDP1L3MBTL1
SCHEMBL3196381 0.73 KDM4E (0.40) KDM4ETDP1L3MBTL1
SCHEMBL3196385 0.73 KDM4E (0.40) KDM4ETDP1L3MBTL1
SCHEMBL11571255 0.73 SIRT2 (0.32) KDM4E
SCHEMBL11584078 0.73 SIRT2 (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4089491-A None JP disclosed
JP-H0489491-A ACID ANHYDRIDE GROUP-CONTAINING SILANE COMPOUND AND ITS PRODUCTION SHIN ETSU CHEM CO LTD 1992-03-23 JP disclosed