SCHEMBL9618281

SCHEMBL9618281

COc1ccc(COc2ccc(Cl)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.67
MAOB P27338 6/20 0.67
MAOA P21397 1/20 0.62
NR4A2 P43354 1/20 0.59
NPC1 O15118 1/20 0.59
POLB P06746 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MAPT P10636 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000873 0.89 APP (0.80) APPMAOBNPC1POLBRAB9A
SCHEMBL10991891 0.89 MAOB (0.80) APPMAOBMAOANR4A2NPC1
SCHEMBL12330759 0.84 MAOB (0.67) APPMAOBMAOANR4A2NPC1
SCHEMBL5505882 0.84 APP (0.67) APPMAOBNPC1POLBRAB9A
SCHEMBL11121647 0.84 MAOB (0.67) APPMAOBMAOANR4A2NPC1
SCHEMBL28784521 0.84 APP (0.67) APPMAOBNPC1POLBRAB9A
SCHEMBL7176444 0.84 MAOB (0.67) APPMAOBMAOANR4A2NPC1
SCHEMBL257760 0.84 MAOB (0.67) APPMAOBMAOANR4A2NPC1
SCHEMBL791305 0.82 MAOB (0.73) APPMAOBMAOANR4A2NPC1
SCHEMBL11600066 0.82 MAOB (0.69) APPMAOBMAOANR4A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2235832-A None JP disclosed
JP-4089284-A None JP disclosed
JP-H0489284-A THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1992-03-23 JP disclosed
JP-H02235832-A PREPARATION OF ARALKYL ARYL ETHER FUJI PHOTO FILM CO LTD 1990-09-18 JP disclosed