Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618443 | 0.92 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL9618442 | 0.92 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL18458288 | 0.83 | HCAR2 (0.41) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL868946 | 0.83 | TSHR (0.43) | GAA | |
| SCHEMBL9328076 | 0.82 | ATM (0.40) | HCAR2KEAP1NFE2L2GAAATM | |
| SCHEMBL4583814 | 0.82 | ATM (0.40) | HCAR2KEAP1NFE2L2GAAATM | |
| SCHEMBL4583805 | 0.82 | ATM (0.40) | HCAR2KEAP1NFE2L2GAAATM | |
| SCHEMBL8099897 | 0.80 | HCAR2 (0.33) | HCAR2KEAP1NFE2L2GAAATM | |
| SCHEMBL16256527 | 0.78 | HCAR2 (0.37) | HCAR2KEAP1NFE2L2GAAATM | |
| SCHEMBL7949513 | 0.78 | ATM (0.47) | HCAR2KEAP1NFE2L2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4332704-A | — | — | None | — | — | JP | disclosed |
| US-8895691-B2 | Acid-labile polymers and monomers for their construction | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895691-B2 | Acid-labile polymers and monomers for their construction | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-11-25 | — | — | US | disclosed |
| US-20110152496-A1 | ACID-LABILE POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152496-A1 | ACID-LABILE POLYMERS AND MONOMERS FOR THEIR CONSTRUCTION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-06-23 | — | — | US | disclosed |
| JP-H04332704-A | HYDROUS SOFT CONTACT LENS | NIPPON OIL & FATS CO LTD | 1992-11-19 | — | — | JP | disclosed |