Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.92 |
| ▸ | CA2 | P00918 | 4/20 | 0.92 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.92 |
| ▸ | CA9 | Q16790 | 3/20 | 0.92 |
| ▸ | CA3 | P07451 | 3/20 | 0.92 |
| ▸ | CA4 | P22748 | 3/20 | 0.92 |
| ▸ | CA1 | P00915 | 2/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.92 |
| ▸ | GLA | P06280 | 1/20 | 0.92 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CA5A | P35218 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL11521502 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL11441681 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL27403553 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL127451 | 1.00 | — | — | |
| Phenol SCHEMBL30012101 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL271207 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL11521497 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL11441685 | 1.00 | — | — | |
| Phenol SCHEMBL28338962 | 0.96 | CA12 (0.85) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL14954052 | 0.96 | CA12 (0.85) | CA12CA2CA14CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113462123-A | Material composition for COB (chip on Board) packaged LED (light-emitting diode) | 巴中市特兴智能科技有限公司 | 2021-10-01 | — | — | CN | claimed |
| JP-4337531-A | — | — | None | — | — | JP | disclosed |
| EP-2912104-B9 | CONCENTRATED POLYMERIC COMPOSITIONS OF VINYL AROMATIC POLYMERS AND/OR VINYL AROMATIC COPOLYMERS | VERSALIS SPA (IT) | 2021-05-26 | — | — | EP | disclosed |
| EP-2912104-B2 | CONCENTRATED POLYMERIC COMPOSITIONS OF VINYL AROMATIC POLYMERS AND/OR VINYL AROMATIC COPOLYMERS | VERSALIS SPA (IT) | 2020-07-22 | — | — | EP | disclosed |
| US-9914827-B2 | Concentrated polymeric compositions of vinyl aromatic polymers and/or copolymers | VERSALIS S.P.A. (IT) | 2018-03-13 | — | — | US | disclosed |
| EP-2912104-B1 | CONCENTRATED POLYMERIC COMPOSITIONS OF VINYL AROMATIC POLYMERS AND/OR VINYL AROMATIC COPOLYMERS | VERSALIS SPA (IT) | 2017-09-06 | — | — | EP | disclosed |
| US-20150259521-A1 | Concentrated Polymeric Compositions of Vinyl Aromatic Polymers and/or Copolymers | Versalis S.P.A, (IT) | 2015-09-17 | — | — | US | disclosed |
| EP-2912104-A1 | CONCENTRATED POLYMERIC COMPOSITIONS OF VINYL AROMATIC POLYMERS AND/OR COPOLYMERS | Versalis S.p.A (IT) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014063993-A1 | CONCENTRATED POLYMERIC COMPOSITIONS OF VINYL AROMATIC POLYMERS AND/OR COPOLYMERS | VERSALIS S.P.A (IT) | 2014-05-01 | — | — | WO | disclosed |
| US-20120129414-A1 | THERMOSETTING RESIN COMPOSITION AND PREPREG OR LAMINATE USING THE SAME | UNIPLUS ELECTRONICS CO., LTD. (TW) | 2012-05-24 | — | — | US | disclosed |
| JP-H04337531-A | OPTICAL RECORDING MEDIUM | MITSUI TOATSU CHEM INC | 1992-11-25 | — | — | JP | disclosed |