SCHEMBL9618472

SCHEMBL9618472

CCOC(=O)COc1cccc2c1CCC(C=NOC(c1ccccc1)c1ccccc1)C2

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 18/20 0.62
TBXAS1 P24557 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9005740 0.89 PTGIR (0.77) PTGIRTBXAS1
SCHEMBL9005753 0.89 PTGIR (0.77) PTGIRTBXAS1
SCHEMBL9005710 0.84 PTGIR (0.82) PTGIRTBXAS1
SCHEMBL9005703 0.84 PTGIR (0.82) PTGIRTBXAS1
SCHEMBL9005622 0.81 PTGIR (0.64) PTGIRTBXAS1
SCHEMBL9005706 0.81 PTGIR (0.47) PTGIR
SCHEMBL7778511 0.79 CA1 (0.53) PTGIRTBXAS1
SCHEMBL9005816 0.79 PTGIR (0.72) PTGIRTBXAS1
SCHEMBL9005776 0.79 PTGIR (0.72) PTGIRTBXAS1
SCHEMBL9129205 0.78 PTGIR (0.59) PTGIRTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4334358-A None JP disclosed
JP-H04334358-A CONDENSED BENZENEOXY ACETIC ACID DERIVATIVE ONO PHARMACEUT CO LTD 1992-11-20 JP disclosed