Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.84 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.84 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.64 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | ATIC | P31939 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747580 | 0.91 | HMGB1 (1.00) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL11558714 | 0.88 | HMGB1 (0.65) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9748865 | 0.87 | PTPN1 (0.64) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9978783 | 0.86 | HMGB1 (0.67) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL27785282 | 0.83 | HMGB1 (0.77) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL28707306 | 0.83 | PTPN1 (0.73) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL20412252 | 0.81 | HMGB1 (0.75) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL27948910 | 0.81 | HMGB1 (0.56) | HMGB1CXCL12HPGDTSHRALDH1A1 | |
| SCHEMBL9978678 | 0.81 | HMGB1 (0.63) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL28184826 | 0.80 | HMGB1 (0.73) | HMGB1CXCL12PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575454-B1 | NAPHTHALENE CARBOXAMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2018-08-29 | — | — | EP | claimed |
| EP-2575454-B1 | NAPHTHALENE CARBOXAMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2018-08-29 | — | — | EP | disclosed |
| US-7402380-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7402380-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-5141557-A | Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0283924-B1 | AQUEOUS SUSPENSION AND PREPARATION METHOD THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4997874-A | Dispersion of metal-modified salicylic acid resin | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0283924-A2 | Aqueous suspension and preparation method thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4134847-A | HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4046941-A | PRESSURE SENSITIVE COPYING | SANKO CHEMICAL COMPANY LTD. (JA) | 1977-09-06 | — | — | US | disclosed |