Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77672 | 0.89 | MAPT (0.50) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Potassium Ion SCHEMBL3894341 | 0.89 | MAPT (0.44) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| SCHEMBL11337925 | 0.84 | KDM4E (0.47) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Nitrilotriacetic Acid SCHEMBL23358712 | 0.82 | KDM4E (0.52) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| SCHEMBL20446674 | 0.80 | KDM4E (0.44) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| SCHEMBL30689662 | 0.79 | KDM4E (0.69) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Edetic Acid SCHEMBL6766678 | 0.77 | KDM4E (0.68) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Nitrilotriacetic Acid SCHEMBL10985194 | 0.76 | KDM4E (0.54) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Nitrilotriacetic Acid SCHEMBL10890157 | 0.76 | KDM4E (0.52) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 | |
| Nitrilotriacetic Acid SCHEMBL1284701 | 0.76 | KDM4E (0.59) | MAPTKDM4EALOX15SMN1; SMN2FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132323-A | Treatment of animals | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0333756-B1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-01-15 | — | — | EP | disclosed |
| US-5011959-A | 1,2-diaminocyclohexane-platinum complexes with antitumor activity | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0333756-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY. | UNIV TEXAS (US) | 1989-09-27 | — | — | EP | disclosed |
| WO-1988003925-A1 | 1,2-DIAMINOCYCLOHEXANE-PLATINUM COMPLEXES WITH ANTITUMOR ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1988-06-02 | — | — | WO | disclosed |