Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP18 | Q9UMW8 | 2/20 | 0.67 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.59 |
| ▸ | F3 | P13726 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619484 | 1.00 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL812720 | 0.88 | AKR1C3 (0.60) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL809473 | 0.88 | AKR1C3 (0.60) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL3437943 | 0.85 | USP18 (0.56) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL29169528 | 0.85 | USP18 (0.56) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL3437940 | 0.85 | USP18 (0.56) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL29506224 | 0.84 | USP18 (0.52) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL14797847 | 0.83 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL14797848 | 0.83 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL18610094 | 0.80 | USP18 (0.50) | USP18UCHL5HSP90AA1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141976-A | MIXTURES OF POLYARYLENE SULPHIDES, NITROARYLMETHYLIDENE KETONES, GLASS FIBERS AND OPTIONALLY OTHER FILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| EP-0472034-A1 | Mixtures of polyarylene sulfides, nitroaryl methylide ketones, glass fibres, and optionally further fillers | BAYER AG (DE) | 1992-02-26 | — | — | EP | disclosed |
| US-4354976-A | Process for the preparation of azidobenzal compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-19 | — | — | US | disclosed |