Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.77 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.77 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.77 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.68 |
| ▸ | AMD1 | P17707 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394817 | 0.90 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12801404 | 0.90 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16128949 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9940610 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12928304 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL460251 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL460252 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12899828 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL10001405 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL17108374 | 0.88 | PI4KA (0.82) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047982-A2 | USE OF ADENOSINE AND/OR OF ONE OF ITS DERIVATIVES AS AGENT FOR THE TREATMENT OF HUMAN PERSPIRATION | L'OREAL (FR) | 2011-04-28 | — | — | WO | disclosed |
| EP-0269574-B1 | NOVEL ADENOSINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS AN ACTIVE INGREDIENT | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4843066-A | HYPOTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |