SCHEMBL9620489

SCHEMBL9620489

FC(F)=C(F)C(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C12F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389983 0.85
SCHEMBL38662617 0.83
SCHEMBL1279986 0.69 MEN1 (0.50) MEN1KMT2ATDP1
SCHEMBL1071750 0.69 MEN1 (0.50) MEN1KMT2ATDP1
SCHEMBL144465 0.69 MEN1 (0.50) MEN1KMT2ATDP1
SCHEMBL25327648 0.69 MEN1 (0.50) MEN1KMT2ATDP1
SCHEMBL16700957 0.67 MEN1 (0.47) MEN1KMT2ATDP1
SCHEMBL1332718 0.67 MEN1 (0.47) MEN1KMT2ATDP1
Perfluorocyclobutane SCHEMBL16111781 0.66
SCHEMBL15552407 0.65 MEN1 (0.44) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296661-B1 SINGLE-PHASE COMPOSITION CONTAINING A PERFLUORINATED OIL AND ONE OR MORE SURFACTANT(S), USEFUL AS AN EXCIPIENT FOR COSMETIC AND DERMATOLOGIC FORMULATIONS, AS WELL AS FOR BIOMEDICAL APPLICATIONS ENIRICERCHE S.p.A. (IT) 1992-01-22 EP claimed
US-4942179-A ISOTROPIC OR ANISOTROPIC FORMULATION AND FLUOROPHOSPHATE SURFACTANTS ENIRICHERCHE S.P.A. (IT) 1990-07-17 US claimed
EP-0296661-A2 Single-phase composition containing a perfluorinated oil and one or more surfactant(s), useful as an excipient for cosmetic and dermatologic formulations, as well as for biomedical applications ENIRICERCHE S.p.A. (IT) 1988-12-28 EP claimed
EP-0296661-B1 SINGLE-PHASE COMPOSITION CONTAINING A PERFLUORINATED OIL AND ONE OR MORE SURFACTANT(S), USEFUL AS AN EXCIPIENT FOR COSMETIC AND DERMATOLOGIC FORMULATIONS, AS WELL AS FOR BIOMEDICAL APPLICATIONS ENIRICERCHE S.p.A. (IT) 1992-01-22 EP disclosed
US-4942179-A ISOTROPIC OR ANISOTROPIC FORMULATION AND FLUOROPHOSPHATE SURFACTANTS ENIRICHERCHE S.P.A. (IT) 1990-07-17 US disclosed
EP-0296661-A2 Single-phase composition containing a perfluorinated oil and one or more surfactant(s), useful as an excipient for cosmetic and dermatologic formulations, as well as for biomedical applications ENIRICERCHE S.p.A. (IT) 1988-12-28 EP disclosed