Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620708 | 1.00 | OPRL1 (0.42) | OPRL1SPHK1DRD2SLC6A2HTR2A | |
| SCHEMBL9398896 | 0.92 | SPHK1 (0.43) | OPRL1SPHK1HTR2A | |
| SCHEMBL13666232 | 0.90 | OPRL1 (0.45) | OPRL1 | |
| SCHEMBL12734995 | 0.90 | OPRL1 (0.36) | OPRL1SPHK1DRD2SLC6A2HTR2A | |
| SCHEMBL12739752 | 0.87 | S1PR1 (0.39) | OPRL1SPHK1DRD2SLC6A2HTR2A | |
| SCHEMBL10302097 | 0.87 | OPRL1 (0.37) | OPRL1SPHK1DRD2SLC6A2HTR2A | |
| SCHEMBL12735895 | 0.86 | PDE4B (0.35) | OPRL1SPHK1 | |
| SCHEMBL12716424 | 0.86 | OPRL1 (0.37) | OPRL1SPHK1 | |
| SCHEMBL21321659 | 0.85 | RARB (0.45) | OPRL1SPHK1 | |
| SCHEMBL12734143 | 0.84 | OPRL1 (0.33) | OPRL1SPHK1DRD2SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317587-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |