Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.43 |
| ▸ | HTR2C | P28335 | 8/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620645 | 0.96 | HTR2A (0.42) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620647 | 0.96 | HTR2A (0.42) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620810 | 0.92 | HTR2A (0.43) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9621145 | 0.90 | HTR2A (0.41) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620705 | 0.89 | HTR2A (0.41) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620701 | 0.88 | HTR2A (0.42) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620706 | 0.88 | HTR2A (0.42) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9620951 | 0.88 | HTR2A (0.40) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL10611287 | 0.88 | HTR2A (0.40) | HTR2AHTR2CFFAR1FFAR4KCNH2 | |
| SCHEMBL9621157 | 0.88 | HTR2A (0.40) | HTR2AHTR2CFFAR1FFAR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283490-B1 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-01-08 | — | — | EP | disclosed |
| EP-0283490-A1 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1988-09-28 | — | — | EP | disclosed |
| WO-1988002364-A2 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-04-07 | — | — | WO | disclosed |