Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621084 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9620578 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9620580 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9620840 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9621143 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9621201 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9621081 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9620837 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL9621197 | 1.00 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL10479810 | 0.99 | DAO (0.39) | DAOCYP3A4CYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283490-B1 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-01-08 | — | — | EP | disclosed |