Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347834 | 0.92 | GAA (0.58) | GAACDK1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL54922 | 0.92 | GAA (0.58) | GAACDK1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL2320176 | 0.91 | GAA (0.57) | GAACDK1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL10670437 | 0.86 | GAA (0.52) | GAACDK1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL7157074 | 0.84 | GAA (0.57) | GAACDK1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL10847825 | 0.83 | GAA (0.53) | GAACDK1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL10861755 | 0.82 | GAA (0.54) | GAACDK1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL28716162 | 0.81 | GAA (0.54) | GAACDK1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL6906049 | 0.80 | GAA (0.56) | GAACDK1CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL11121612 | 0.78 | TSHR (0.69) | GAATSHRSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4601747-A | N-alkoxyaminosulfonylureas and N-alkylsulfonylaminosulfonylureas and pyrimidino thiadiazine oxides as herbicides and plant growth-regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-22 | — | — | US | claimed |
| US-5157121-A | Reaction of alkyl(n-alkylsulfonyl-n-alkylamino)sulfonyl carbamates with 2-aminopyrimidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| US-5155222-A | PROCESS FOR THE PREPARATION OF N-ALKYLSULFONYLAMINOSULFONYLUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| US-4718937-A | HERBICIDES, PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| US-4601747-A | N-alkoxyaminosulfonylureas and N-alkylsulfonylaminosulfonylureas and pyrimidino thiadiazine oxides as herbicides and plant growth-regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-22 | — | — | US | disclosed |