Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | FRK | P42685 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621932 | 0.90 | KDR (0.56) | ARGRM4NPC1CCR2CCR5 | |
| SCHEMBL10612883 | 0.89 | NPC1 (0.50) | NPC1PKMRAB9AKDRMEN1 | |
| SCHEMBL11619037 | 0.88 | KDR (0.66) | GRM4RAB9AKDRMEN1KMT2A | |
| SCHEMBL11622735 | 0.88 | MAPT (0.57) | ARNPC1PKMRAB9AKDR | |
| SCHEMBL11301649 | 0.83 | MEN1 (0.55) | NPC1PKMRAB9AMEN1KMT2A | |
| SCHEMBL7607258 | 0.82 | MAPT (0.62) | RAB9ACCR2KDRMEN1KMT2A | |
| SCHEMBL30499684 | 0.82 | MAPT (0.62) | RAB9ACCR2KDRMEN1KMT2A | |
| Penfluron SCHEMBL117735 | 0.82 | EPHX2 (0.60) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL10613743 | 0.81 | NPC1 (0.57) | NPC1RAB9AKDRMEN1KMT2A | |
| SCHEMBL9728577 | 0.81 | MEN1 (0.54) | NPC1PKMRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085226-A | Insecticidal N-(substituted phenyl)-N'-benzoyl ureas | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | claimed |
| US-5096928-A | Caterpillars | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-4782090-A | Benzoyl(thio)urea pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |