Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.80 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP7 | P09237 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | MMP12 | P39900 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622303 | 1.00 | MME (0.80) | MMENAALAD2FOLH1MMP2MMP7 | |
| SCHEMBL11502648 | 0.89 | MME (0.69) | MMENAALAD2FOLH1LTA4H | |
| SCHEMBL8249769 | 0.89 | MME (1.00) | MME | |
| SCHEMBL5869412 | 0.89 | MME (1.00) | MME | |
| SCHEMBL11119164 | 0.89 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11122736 | 0.89 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11122302 | 0.89 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL5869271 | 0.89 | MME (1.00) | MME | |
| SCHEMBL2679035 | 0.89 | MME (1.00) | MME | |
| SCHEMBL2679032 | 0.89 | MME (1.00) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |