SCHEMBL9622787

SCHEMBL9622787

C=C(C)c1cc2ccccc2o1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.60
NPC1 O15118 9/20 0.53
RAB9A P51151 8/20 0.53
MAPK1 P28482 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TSHR P16473 2/20 0.53
MAPT P10636 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
ALDH1A1 P00352 4/20 0.51
HPGD P15428 3/20 0.51
TP53 P04637 3/20 0.49
PKM P14618 2/20 0.49
CASP3 P42574 2/20 0.49
SENP7 Q9BQF6 2/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366547 1.00 FLT3 (0.60) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL8915455 0.83 FLT3 (0.64) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL241548 0.80 FLT3 (0.71) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL31301100 0.78 FLT3 (0.57) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL6272018 0.77 FLT3 (0.56) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL14404773 0.77 FLT3 (0.56) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL10367976 0.77 FLT3 (0.56) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL6272805 0.77 FLT3 (0.67) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL25117245 0.77 FLT3 (0.51) FLT3NPC1RAB9AMAPK1MEN1
SCHEMBL24530041 0.77 FLT3 (0.51) FLT3NPC1RAB9AMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109851507-B Application of scandium-containing rare earth catalyst in catalysis of para-alkylation reaction of aromatic amine 苏州大学 2022-02-01 CN claimed
CN-109503468-B Activation method of perfluoroalkyl carbon halogen bond and method for synthesizing pyridine derivative 南京大学 2020-12-25 CN claimed
CN-109851507-A Application of the rare earth catalyst containing scandium in catalysis aromatic amine contraposition alkylated reaction 苏州大学 2019-06-07 CN claimed
US-4113891-A BENZOFURANS FIRMENICH & CIE (CH) 1978-09-12 US claimed
EP-3609859-B1 CHIRAL METAL COMPLEX COMPOUNDS HOFFMANN LA ROCHE (CH) 2022-04-27 EP disclosed
CN-109851507-B Application of scandium-containing rare earth catalyst in catalysis of para-alkylation reaction of aromatic amine 苏州大学 2022-02-01 CN disclosed
CN-110036047-B Methacrylic copolymer and molded article 株式会社可乐丽 2021-01-05 CN disclosed
US-10875996-B2 Methacrylic copolymer and molded article KURARAY CO., LTD. (JP) 2020-12-29 US disclosed
CN-109503468-B Activation method of perfluoroalkyl carbon halogen bond and method for synthesizing pyridine derivative 南京大学 2020-12-25 CN disclosed
US-20200317902-A1 METHACRYLIC COPOLYMER AND MOLDED ARTICLE KURARAY CO., LTD. (JP) 2020-10-08 US disclosed
CN-106928170-B Dihydrofuranbiphenyl compound and preparation method and application thereof 云南民族大学 2020-05-26 CN disclosed
EP-3564275-A1 METHACRYLIC COPOLYMER AND MOLDED ARTICLE Kuraray Co., Ltd. (JP) 2019-11-06 EP disclosed
US-4085109-A Pyridine sulfur flavoring agents FIRMENICH & CIE (CH) 1978-04-18 US disclosed
US-3989713-A Pyrrylmethylthio flavoring agents FIRMENICH & CIE (CH) 1976-11-02 US disclosed
US-3952026-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3952024-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3943260-A TETRAHYDRO-THIO-PHEN-3-ONES FIRMENICH & CIE (CH) 1976-03-09 US disclosed
US-3931166-A FLAVORANTS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931246-A FURYLALKYL-THIOETHERS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931245-A FURYLALKYLTHIOL CARBOXYLATES FIRMENICH & CIE (CH) 1976-01-06 US disclosed