Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311396 | 1.00 | CYP19A1 (0.68) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL9622954 | 1.00 | CYP19A1 (0.68) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL3130653 | 0.88 | CYP17A1 (0.69) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL27648561 | 0.88 | CYP17A1 (0.69) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL5086100 | 0.86 | CYP19A1 (0.65) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL5086095 | 0.86 | CYP19A1 (0.65) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL5493314 | 0.84 | CYP19A1 (0.73) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL5499393 | 0.84 | CYP19A1 (0.77) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 | |
| SCHEMBL11054839 | 0.82 | CYP19A1 (0.64) | CYP19A1CYP1B1CYP17A1SRD5A2 | |
| SCHEMBL5479309 | 0.82 | CYP19A1 (0.74) | CYP19A1CYP1B1CYP17A1SRD5A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175154-A | Antiobesity, antidiabetic, antilipemic, anticholesterol agents | RESEARCH CORPORATION TECHNOLOGIES, INC. | 1992-12-29 | — | — | US | disclosed |