Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623169 | 1.00 | GSTP1 (0.45) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL1834280 | 0.91 | HPGD (0.43) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL9857324 | 0.91 | HPGD (0.43) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL9623592 | 0.91 | HPGD (0.43) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL11701038 | 0.91 | HPGD (0.43) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL11762132 | 0.90 | TSHR (0.42) | GSTP1HPGDKAT2BTSHRPDE3B | |
| SCHEMBL11105527 | 0.86 | GSTP1 (0.46) | GSTP1TSHRKMT2AALDH1A1 | |
| SCHEMBL11106856 | 0.86 | GSTP1 (0.46) | GSTP1TSHRKMT2AALDH1A1 | |
| SCHEMBL11764316 | 0.85 | TSHR (0.44) | GSTP1HPGDKAT2BTSHRLMNA | |
| SCHEMBL8545969 | 0.84 | GSTP1 (0.44) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319576-B1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1992-01-08 | — | — | EP | disclosed |
| EP-0194144-B1 | PROCESS FOR THE PREPARATION OF 2-ALKYL-CYCLOPENT-2-ENONES | Montedison S.p.A. (IT) | 1991-09-11 | — | — | EP | disclosed |
| EP-0425584-A1 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI- Istituto Biochimico Italiano Giovanni Lorenzini S.p.A. (IT) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990003170-A2 | PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A. (IT) | 1990-04-05 | — | — | WO | disclosed |
| EP-0319576-A1 | PROSTAGLANDIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES. | ISTITUTO BIOCHIMICO ITALIANO (IT) | 1989-06-14 | — | — | EP | disclosed |
| WO-1988010252-A1 | PROSTAGLANDIN DERIVATES, THEIR PROCESS AND PHARMACEUTICAL COMPOSITIONS | IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZIN (IT) | 1988-12-29 | — | — | WO | disclosed |
| US-4673759-A | Process for the preparation of 2-alkyl cyclopent-2-enones | MONTEDISON S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |
| EP-0194144-A2 | Process for the preparation of 2-Alkyl-Cyclopent-2-Enones | Montedison S.p.A. (IT) | 1986-09-10 | — | — | EP | disclosed |