Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623695 | 1.00 | CYP19A1 (0.69) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9623927 | 1.00 | CYP19A1 (0.69) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL10629833 | 0.90 | CYP19A1 (0.59) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9636751 | 0.90 | CYP19A1 (0.72) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9636759 | 0.90 | CYP19A1 (0.72) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL10625656 | 0.88 | CYP19A1 (0.69) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL10625663 | 0.88 | CYP19A1 (0.69) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9458673 | 0.84 | CYP3A4 (0.59) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9458679 | 0.84 | CYP3A4 (0.59) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 | |
| SCHEMBL9458675 | 0.84 | CYP3A4 (0.59) | CYP19A1CYP3A4HIF1ACYP2C9NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749649-A | Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen | THE UPJOHN COMPANY (US) | 1988-06-07 | — | — | US | claimed |
| EP-0127294-B1 | STEROID DEHYDROGENATION | THE UPJOHN COMPANY (US) | 1986-12-17 | — | — | EP | claimed |
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4977255-A | Steroidal 17α-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4921638-A | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one | THE UPJOHN COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0334875-A1 | STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| US-4831131-A | 11β,17α-Dihydroxy-17β-cyano-androstanes | THE UPJOHN COMPANY (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0268400-A1 | Steroidal 17alpha-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| WO-1988003534-A1 | STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1988-05-19 | — | — | WO | disclosed |
| US-4585590-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4548748-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0153001-A2 | Steroids having an enamide or enimide group and their preparation | THE UPJOHN COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4500461-A | Cyanohydrin process | THE UPJOHN COMPANY (US) | 1985-02-19 | — | — | US | disclosed |