Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625987 | 0.96 | RARB (0.48) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9624096 | 0.94 | RARB (0.48) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9625343 | 0.91 | RARB (0.48) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9361291 | 0.90 | RARB (0.50) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9624891 | 0.89 | RARB (0.54) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9625810 | 0.87 | RARB (0.56) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL9236497 | 0.87 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9237681 | 0.87 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9236483 | 0.87 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9240300 | 0.87 | RARB (0.44) | RARBNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255219-B1 | OMEGA-SUBSTITUTED, OPTICALLY ACTIVE 2-ALKANOL ESTER DERIVATIVES | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |