Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647757 | 0.84 | KCNH2 (0.67) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624970 | 0.84 | KCNH2 (0.82) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9624814 | 0.84 | KCNH2 (0.82) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL10645811 | 0.83 | KCNH2 (0.80) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL10644048 | 0.82 | KCNH2 (0.65) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| Methane SCHEMBL10644955 | 0.82 | KCNH2 (0.65) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| Propane SCHEMBL10645441 | 0.82 | KCNH2 (0.65) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| Ethane SCHEMBL10647144 | 0.82 | KCNH2 (0.65) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| Methane SCHEMBL10647628 | 0.82 | KCNH2 (0.65) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| Methane SCHEMBL10647203 | 0.81 | KCNH2 (0.63) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |