Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624607 | 0.98 | RARB (0.48) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7864962 | 0.92 | RARB (0.46) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9624390 | 0.90 | RARB (0.54) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9625734 | 0.90 | RARB (0.50) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9357494 | 0.89 | RARB (0.49) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9625343 | 0.89 | RARB (0.48) | RARBRAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9623890 | 0.88 | RARB (0.54) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9624508 | 0.88 | RARB (0.50) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9625668 | 0.88 | RARB (0.50) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9358052 | 0.87 | RARB (0.49) | RARBRAB9ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255219-B1 | OMEGA-SUBSTITUTED, OPTICALLY ACTIVE 2-ALKANOL ESTER DERIVATIVES | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5047172-A | W-substituted, optically active alkanol ester derivatives | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |