Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624275 | 0.92 | RARB (0.66) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9419088 | 0.86 | TP53 (0.66) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9419104 | 0.86 | MAPK1 (0.61) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL10400837 | 0.83 | TP53 (0.62) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9624358 | 0.83 | MEN1 (0.46) | RARBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9352107 | 0.81 | SMN1; SMN2 (0.52) | RARBMAPTKMT2ATP53TSHR | |
| SCHEMBL9352005 | 0.81 | SMN1; SMN2 (0.52) | RARBMAPTKMT2ATP53TSHR | |
| SCHEMBL9355991 | 0.81 | SMN1; SMN2 (0.52) | RARBMAPTKMT2ATP53TSHR | |
| SCHEMBL9356003 | 0.81 | SMN1; SMN2 (0.52) | RARBMAPTKMT2ATP53TSHR | |
| SCHEMBL9355952 | 0.81 | SMN1; SMN2 (0.52) | RARBMAPTKMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301511-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-5073306-A | Trifluoromethylalkyl substituted | CANON KABUSHIKI KAISHA (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4918213-A | HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0301511-A1 | Optically active compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-02-01 | — | — | EP | disclosed |