SCHEMBL9625437

SCHEMBL9625437

CCCCCCCCOc1ccc(-c2ccc(C=C(F)F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.56
NR5A1 Q13285 1/20 0.54
TP53 P04637 2/20 0.49
TSHR P16473 1/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
PLA2G4B P0C869 1/20 0.48
LTA4H P09960 2/20 0.47
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
RAB9A P51151 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PLA2G4A P47712 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625981 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625048 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625953 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625314 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625871 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9626059 1.00 RARB (0.56) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625001 0.98 RARB (0.54) RARBNR5A1TP53TSHRCYP3A4
SCHEMBL9625283 0.95 CYP2D6 (0.53) RARBNR5A1CYP3A4CYP2D6LTA4H
SCHEMBL9624989 0.89 MEN1 (0.54) RARBCYP3A4CYP2D6LTA4HCYP2C9
SCHEMBL9476769 0.83 RARB (0.54) RARBNR5A1TP53TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325796-B1 A LIQUID CRYSTAL COMPOUND AND A MIXTURE CONTAINING THE SAME Chisso Corporation (JP) 1992-03-11 EP disclosed
US-4877548-A STABLE TO HEAT, LIGHT, ELECTRICITY AND MOISTURE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0325796-A1 A liquid crystal compound and a mixture containing the same Chisso Corporation (JP) 1989-08-02 EP disclosed