SCHEMBL9625655

SCHEMBL9625655

Cc1cc(=O)cc(CO)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.58
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
KDM4E B2RXH2 10/20 0.38
ALDH1A1 P00352 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
POLB P06746 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
TYR P14679 1/20 0.36
DAO P14920 1/20 0.36
MAPT P10636 2/20 0.33
CASP1 P29466 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176772 0.80 NQO1 (0.61) NQO1MEN1KMT2AGLACYP3A4
SCHEMBL9574935 0.78 NQO1 (0.58) NQO1MEN1KMT2AGLACYP3A4
SCHEMBL9586 0.75
Hydrochloric Acid SCHEMBL10821353 0.73 NQO1 (0.94) NQO1MEN1KMT2AGLACYP3A4
SCHEMBL4701222 0.71 NQO1 (0.48) NQO1GLAKDM4EALDH1A1L3MBTL1
SCHEMBL918518 0.70
SCHEMBL10961859 0.70 MAPT (0.62) MEN1KMT2AGLACYP3A4KDM4E
SCHEMBL5179572 0.69 KDM4E (0.35) MEN1KMT2AGLAKDM4EALDH1A1
SCHEMBL183308 0.67
SCHEMBL3555239 0.67 KDM4E (0.54) MEN1KMT2AKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473764-A1 METAL COMPLEXES Hider, Robert Charles (GB) 1992-03-11 EP disclosed
WO-1991014664-A1 METAL COMPLEXES HIDER ROBERT CHARLES (GB) 1991-10-03 WO disclosed