Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407225 | 0.82 | PPARA (0.69) | PPARACTSSPPARGSYKATM | |
| SCHEMBL273467 | 0.81 | PPARA (0.58) | PPARACTSSPPARGSYKATM | |
| SCHEMBL1001282 | 0.80 | PPARA (0.63) | PPARACTSSPPARGSYKATM | |
| SCHEMBL272967 | 0.80 | PPARA (0.63) | PPARACTSSPPARGSYKATM | |
| SCHEMBL1000339 | 0.80 | PPARA (0.63) | PPARACTSSPPARGSYKATM | |
| SCHEMBL25467757 | 0.79 | PPARA (0.65) | PPARACTSSPPARGSYKATM | |
| SCHEMBL212796 | 0.79 | PPARA (0.65) | PPARACTSSPPARGSYKATM | |
| SCHEMBL1132570 | 0.79 | PPARA (0.65) | PPARACTSSPPARGSYKATM | |
| SCHEMBL27538401 | 0.79 | ATM (0.65) | PPARACTSSPPARGSYKATM | |
| SCHEMBL212797 | 0.79 | PPARA (0.65) | PPARACTSSPPARGSYKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299795-B1 | AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |