SCHEMBL9626041

SCHEMBL9626041

CCc1ccc(-c2ccc(CCC=C(F)F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
EGFR P00533 1/20 0.38
HRH3 Q9Y5N1 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
RARB P10826 6/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
ALDH1A1 P00352 2/20 0.34
UCHL1 P09936 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR5 Q9H228 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CYP2C9 P11712 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
RARA P10276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9624346 0.89 MCL1 (0.41) LPLLIPGRARBALDH1A1NPC1
SCHEMBL9625570 0.86 RARB (0.51) EGFRRARBALDH1A1CYP2C9MEN1
SCHEMBL15870432 0.85 RARB (0.41) TAAR1RARBS1PR1RARAFAAH
SCHEMBL9625858 0.85 CYP1A2 (0.41) TAAR1HRH3L3MBTL1GPR84S1PR1
SCHEMBL9624964 0.84 RARB (0.53) EGFRHRH3LPLLIPGRARB
SCHEMBL14027713 0.83 MAOB (0.50) TAAR1
SCHEMBL9626098 0.83 FFAR1 (0.48) TAAR1GPR84
SCHEMBL9625413 0.83 RARB (0.54) EGFRLPLLIPGRARBALDH1A1
SCHEMBL9625021 0.83 RARB (0.54) EGFRLPLLIPGRARBALDH1A1
SCHEMBL10540994 0.83 RARB (0.54) EGFRLPLLIPGRARBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325796-B1 A LIQUID CRYSTAL COMPOUND AND A MIXTURE CONTAINING THE SAME Chisso Corporation (JP) 1992-03-11 EP disclosed
US-4877548-A STABLE TO HEAT, LIGHT, ELECTRICITY AND MOISTURE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0325796-A1 A liquid crystal compound and a mixture containing the same Chisso Corporation (JP) 1989-08-02 EP disclosed